Symptoms

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Symptoms of chronic lymphocytic leukaemia (CLL)

CLL tends to progress slowly and many people with CLL may not experience symptoms for years. Symptoms of CLL can also be linked to many other conditions, making it difficult to self-detect the disease without proper testing.

The most common symptoms include:

  • Frequent infections
  • Anaemia: persistent tiredness, shortness of breath, and pale skin
  • Weight loss
  • Night sweats
  • Fever
  • Bleeding and bruising more easily than normal
  • Abdominal swelling and discomfort
  • Swollen glands in the neck, armpits, and groin

CLL is often detected during routine check-ups and blood tests for other health problems, as the cancerous cells can be easily detected in the blood.

Unlike bowel or breast cancer, it’s not common practice to routinely screen for CLL, but it is important to contact your doctor as soon as you experience any of the mentioned symptoms or any other changes in your health.

References

Memorial Sloan Kettering Cancer Center. Multiple Myeloma Symptoms. https://www.mskcc.org/cancer-care/types/multiple-myeloma/multiple-myeloma-symptoms. Last accessed: February 2025.
American Cancer Society. Non-medical treatments for pain. https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/pain/non-medical-treatments-for-cancer-pain.html. Last accessed: February 2025.
Yong K, et al. Br J Haematol. 2016;175:252–264.
Snowden JA, et al. Br J Haematol. 2011;154:76–103.
Drugs.com. Multiple Myeloma. Available at: https://www.drugs.com/cg/multiple-myeloma.html. Last accessed: February 2025.
Myeloma UK. Fatigue infoguide. Available at: www.myeloma.org.uk/wp-content/uploads/2018/03/Myeloma-UK-Fatigue-Infoguide.pdf. Last accessed: February 2025.
Multiple Myeloma Research Foundation website. Symptoms, side effects and complications. http://www.myeloma.org/sites/default/files/images/publications/UnderstandingPDF/concisereview.pdf. Last accessed: February 2025.
Myeloma UK. Myeloma and the kidney infoguide. Available at: www.myelomaorg.uk/wp-content/uploads/2018/03/Myeloma-UK-Kidney-Infoguide.pdf. Last accessed: February 2025.
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